Elective withdrawal of mycophenolate mofetil in renal transplant recipients treated with mycophenolate mofetil, cyclosporine, and prednisone
نویسندگان
چکیده
منابع مشابه
BENEFICIAL EFFECT OF LOW DOSE CYCLOSPORINE WITH MMF (MYCOPHENOLATE MOFETIL) IN RENAL ALLOGRAFT RECIPIENTS
Background: Calcineurin inhibitors (CNI) have significantly reduced the incidence of acute rejection. Nephrotoxicity however may contribute to long-term allograft dysfunction. Mycophenolate mofetil (MMF) may allow cyclosporine (CsA) dose reduction without increasing the risk of rejection. Methods: In seventy-eight living unrelated kidney transplant patients with renal dysfunction, we studi...
متن کاملLow-dose and rapid steroid withdrawal in renal transplant patients treated with tacrolimus and mycophenolate mofetil.
CORTICOSTEROIDS HAVE PROVED to be very effective for the immunosuppressive treatment of organ transplant patients, but unfortunately they are responsible for many undesirable side effects, such as cataracts, delayed growth in children, skin fragility, bone diseases, and other manifestations considered to be cardiovascular risk factors, such as glucose intolerance, arterial hypertension, and dys...
متن کاملThe use of mycophenolate mofetil in liver transplant recipients.
Mycophenolate mofetil is an important drug in the modern immunosuppressive arsenal. Mycophenolate mofetil is the semisynthetic morpholinoethyl ester of mycophenolate acid. Mycophenolate acid prevents T and B cell proliferation by specifically inhibiting a purine pathway required for lymphocyte division. This paper extensively reviews the experience of mycophenolate mofetil use in liver transpla...
متن کاملbeneficial effect of low dose cyclosporine with mmf (mycophenolate mofetil) in renal allograft recipients
background: calcineurin inhibitors (cni) have significantly reduced the incidence of acute rejection. nephrotoxicity however may contribute to long-term allograft dysfunction. mycophenolate mofetil (mmf) may allow cyclosporine (csa) dose reduction without increasing the risk of rejection. methods: in seventy-eight living unrelated kidney transplant patients with renal dysfunction, we studied th...
متن کاملComparing outcomes associated with dose manipulations of enteric-coated mycophenolate sodium versus mycophenolate mofetil in renal transplant recipients.
BACKGROUND This study assessed the incidence of reported gastrointestinal (GI) complications in patients treated with enteric-coated mycophenolate sodium (EC-MPS) versus mycophenolate mofetil (MMF) and to examine the impact of dose manipulations on biopsy-proven acute rejection (BPAR). METHODS A retrospective study was conducted in 379 renal transplant recipients initiated on EC-MPS or MMF th...
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ژورنال
عنوان ژورنال: Transplant International
سال: 2001
ISSN: 0934-0874,1432-2277
DOI: 10.1111/j.1432-2277.2001.tb00021.x